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To Biopsy or Not? ๐Ÿ’‰

Many cases have been reported in the medical literature on "seeding," which is the spreading of cancer cells after biopsy or surgery. A search in any medical database can pull up many reports of such:


However! Spontaneous remission from cancer has also been reported in many cases following biopsy or partial removal of a tumor:


In our series, 24% of NMSCs transected on the initial biopsy showed no residual tumor in the excision specimens, implying that some event in the interval between biopsy and excision may lead to the eradication of residual tumor. The exact mechanism is unclear, but wound healing likely plays an important role.


Search: "spontaneous biopsy remission" on PubMed:

(Not cancer, and in dogs, but very interesting nonetheless!)

"Two weeks after a biopsy, the skin lesion spontaneously regressed without any specific treatment. In non-immunocompromised dogs, CPV-2-related footpad papillomatosis could spontaneously resolve after a biopsy."

"We describe the first known report of spontaneous resolution of a congenital GBM without any systemic therapy. A limited debulking procedure was performed at diagnosis, and the residual tumor underwent spontaneous resolution over the following 21 months. The patient remains in remission, with no tumor recurrence after 5 years of follow-up."


So when you're faced with a decision to biopsy or not, consider first the state of your immune system.


Why do cancer cells behave in this way?


There is interesting research on the metabolism of cancer cells that are metastasizing are actually changing their metabolism: The metabolism of cancer cells during metastasis






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