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Cannabis

My personal stance is that I recommend CBD products for nausea and pain relief without THC due to THC's psychotropic effects. There is also some question whether CBD can lead to liver toxicity when taken in conjunction with some pharmaceutical drugs. I am not sure of the frequency of this or if it can be alleviated with coffee enemas. If you have any questions or comments on this please email me! contact@baileyobrien.com. Thanks!

Review Article - A User’s Guide to Cannabinoid Therapies in Oncology

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176373/pdf/conc-23-398.pdf

Study - Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer

https://www.researchgate.net/publication/333052937_Cannabidiol_Enhances_the_Therapeutic_Effects_of_TRAIL_by_Upregulating_DR5_in_Colorectal_Cancer

"Cannabidiol, a major non-psychotomimetic compound derived from Cannabis sativa, is a potential therapeutic agent for a variety of diseases such as inflammatory diseases, chronic neurodegenerative diseases, and cancers. Here, we found that the combination of cannabidiol and TNF-related apoptosis-inducing ligand (TRAIL) produces synergistic antitumor effects in vitro. However, this synergistic effect was not observed in normal colonic cells. The levels of ER stress-related proteins, including C/EBP homologous protein (CHOP) and phosphorylated protein kinase RNA-like ER kinase (PERK) were increased in treatment of cannabidiol. Cannabidiol enhanced significantly DR5 expression by ER stress. Knockdown of DR5 decreased the combined effect of cannabidiol and TRAIL. Additionally, the combination of TRAIL and cannabidiol decreased tumor growth in xenograft models. Our studies demonstrate that cannabidiol enhances TRAIL-induced apoptosis by upregulating DR5 and suggests that cannabidiol is a novel agent for increasing sensitivity to TRAIL."

Article - Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226605/

 

Article - Can THC and CBD Really Help with Nausea and Vomiting?

https://www.cbdschool.com/can-thc-and-cbd-really-help-with-nausea-and-vomiting/

Study - Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent

https://www.medicinalgenomics.com/wp-content/uploads/2013/01/Bergamaschi_2011.pdf?fbclid=IwAR1InfA9JzCXO3M9q3SW6vICcoQpArDy55zNjKYGXiBxc6VszSRW_UpeTLY

Furthermore, CBD can inactivate human P450 3A4 [111], which is responsible for metabolizing more than 60% of clinically prescribed drugs [112]"

Meta Analysis - Safety and Toxicology of Cannabinoids

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604177/pdf/13311_2015_Article_380.pdf

Sources in California:

Green Health Consultants

Cannakids 

Aunt Zeldas

Here is a company that uses third party safety testing: 

GreenSpectrums

I checked out the lab that does the testing and as far as I can see they look legit:  https://terpenesandtesting.com/cannabis-testing-lab-dvt/

 

It looks like this product from Green Spectrums might be the best one to start with since it contains a low dose: 

https://greenspectrums.com/product/250mg-hemp-oil-tincture-natural-flavor/

 

I saw in this video that it would be best to start with 5-10mg of CBD, and one dropper full of the tincture above (the 250mg bottle) provides 8.33mg of CBD. However, the bottle only contains 30 servings so it might be better to get the 500mg bottle and you could do 1/3 the dropper to get 5mg of CBD and it would last you longer. 

Article: CBD Lab Reports: Why They Are Important & How to Read Them

https://bigskybotanicals.com/education/how-to-read-cbd-lab-reports/

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