PABA: An Antifungal Melanoma Treatment? 🧫

August 13, 2019

 

Hi Friend! 

 

The other day I posted something on my Facebook page that was quite popular, and since you may not be on FB (Facebook) I thought I should share this with you here! Here's what I said:

 

"Hey all! I share in some of my interviews and on my website that PABA is a B vitamin I started taking the night my oncologist suggested it, after she discovered that PABA somehow seemed to kill melanoma cells in her lab. I noticed shrinkage of the cancer after starting this and a redox signaling supplement (as well as Temodar, a chemo pill, last-minute) before starting the Gerson Therapy and Coley's toxins in Mexico. 

 

Well, I've found another study about PABA, how it helps protect pepper plants from bacterial and viral infections and grow better than their "peers!" :) Interesting stuff.

 

Here's the study: The folate precursor para-aminobenzoic acid elicits induced resistance against Cucumber mosaic virus and Xanthomonas axonopodis.
"Unexpectedly, fruit yield was increased in PABA-treated plants, indicating that PABA-mediated SAR successfully protected pepper plants from infection by bacterial and viral pathogens without significant fitness allocation costs."


https://www.ncbi.nlm.nih.gov/pubmed/23471007 "

 

PABA has been has been shown to be an antiviral agent in multiple studies, including this other one: Production of Antifungal p-Aminobenzoic Acid in Lysobacter antibioticus OH13.

 

https://pubs.acs.org/doi/suppl/10.1021/acs.jafc.7b05084/suppl_file/jf7b05084_si_001.pdf

 

You can see in the photos how the fungal colonies reduced in size! So cool!! :)

 

This last study on PABA suggests that clinically it may be helpful in melanoma treatment. It was written by a former oncologist of mine who recommended PABA to me. I haven't been able to get the full text of the article, though I've requested it and may have it in the future to do further reading and evaluation:

Modulation of chemotherapy with para-amino benzoic acid (PABA): Translation from preclinical models to a completed phase I trial

https://ascopubs.org/doi/abs/10.1200/jco.2005.23.16_suppl.7557 

 

In the abstract the author recalls from previous study that melanoma cells (of the B16F10 line) exposed to PABA had a lessening or loss of pigmentation. (Maybe this is what she meant when she told me that they died in the petri dishes??) The author then stated that studies of mice with the same line of melanoma cells that received daily doses of PABA and Paclitaxel, a chemothereutic agent, showed differences compared to both the control group (receiving no treatment whatsoever) and the group receiving solely Paclitaxel. Meaning, PABA enhanced the efficacy of Paclitaxel in that melanoma line.

 

This study evaluated how patients responded to treatment with PABA, Paclitaxel and Carboplatin, who first failed treatment with Dacarbazine (DTIC). The results were not detailed, except that some patients experienced clinical responses, and warranted further study in a phase II trial. Meaning, PABA was safe enough to be considered for further study! Yay!

 

So, is there a viral connection to melanoma? Did it help put my melanoma into remission? Would it be helpful for most melanoma patients? I'm not sure, but it would be great to find out! If you have melanoma, it might be worth asking your doctor (or health coach) about. If you decide to try it, please let me know! I'd like to know how it goes.Thank goodness it was one of the least expensive parts of my protocol, at about $12 for a one-month supply, so it shouldn't break the bank if you decide it's right for you to try!! 😁👏 

 

Finally! Last of all for tonight... 😉 If you read my last email from a couple days ago, you read that Chris Wark's Square One online cancer coaching program is airing beginning tonight at 9pm eastern time! Just a couple hours away... It's free, informative, soothing in some ways, inspiring in others and overall it's awesome! 😁 People are having some great results on it, which you can read about here!

 

Here's the link if you need it again. Have a happy, healthy evening, Friend! Talk to you soon!

 

Blessings,

 

Bailey 🌸

 

Ephesians 3:20-21 Now to Him who is able to do far more abundantly beyond all that we ask or think, according to the power that works within us, to Him be the glory in the church and in Christ Jesus to all generations forever and ever. Amen.

 

Photo by Drew Hays on Unsplash

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